Dosage & Administration

• In patients with mild hypercalcemia and few symptoms, a lower dosage of 100 mg/m²/day for 5 days may be considered
  
  
• If serum calcium levels are lowered into the normal range in less than 5 days, treatment may be discontinued early
  
  
• The daily dose must be administered as an intravenous infusion over 24 hours
  
  
• Ganite should be diluted in 1000 mL of normal saline or 5% dextrose solution injection
  
  
  • Solution is stable for 48 hours at room temperature (15°-30°C) or for 7 days if stored under refrigeration (2°-8°C).
  • Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit
    
    
• Adequate hydration must be maintained before and during the treatment period with careful attention to avoid overhydration in patients with compromised cardiovascular status.
  
  
• The safety and efficacy of subcutaneous administration (see Drug Interactions section of the Full Prescribing Information) or retreatment with Ganite has not been established